Brufen

More Than Just a Painkiller

Pain is often accompanied by inflammation, which can cause swelling, stiffness and reduced movement. Whether it is a sprained ankle, severe toothache or painful arthritis, treating the inflammation as well as the pain can help speed recovery and improve daily comfort. Brufen 400 mg Tablet is widely prescribed because it targets both problems at the same time.

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What Is Brufen 400 mg?

Brufen 400 mg contains ibuprofen, a well-established non-steroidal anti-inflammatory drug (NSAID). It is used to relieve mild to moderate pain, reduce inflammation and lower fever in adults and adolescents when appropriate.

Unlike medicines that only relieve pain, Brufen also helps control the inflammatory process responsible for swelling, redness and stiffness. This makes it useful for a wide range of acute injuries as well as chronic inflammatory conditions.

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How Brufen Helps Relieve Pain

When the body is injured or affected by inflammation, it produces substances called prostaglandins. These chemicals contribute to pain, swelling and fever.

Brufen works by blocking the enzymes (COX-1 and COX-2) involved in prostaglandin production. As prostaglandin levels decrease, pain becomes less intense, inflammation settles and body temperature returns towards normal.

For many people, symptom relief begins within 30 to 60 minutes, although the exact timing varies depending on the individual and the condition being treated.

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When Doctors Commonly Prescribe Brufen

Brufen 400 mg may be recommended for many painful and inflammatory conditions, including:

• Muscle strains and sports injuries.
• Back pain and neck pain.
• Osteoarthritis and rheumatoid arthritis.
• Dental pain following tooth extraction or dental procedures.
• Headaches and migraine attacks.
• Painful menstrual cramps.
• Joint pain and stiffness.
• Tendon and ligament injuries.
• Fever associated with infections.

The medicine helps improve comfort but does not treat the underlying cause of infections or chronic diseases.

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Using Brufen Safely

Like all NSAIDs, Brufen should be used only when necessary and for the shortest duration needed to control symptoms. Taking higher doses or using it for prolonged periods may increase the risk of stomach ulcers, gastrointestinal bleeding, kidney impairment and cardiovascular complications.

To reduce stomach irritation, Brufen is usually taken with food or immediately after a meal. Drinking plenty of water while taking the medicine may also help maintain normal kidney function, particularly during illness or hot weather.

People with a history of stomach ulcers, asthma triggered by NSAIDs, kidney disease, liver disease, heart disease or high blood pressure should speak to their healthcare professional before using Brufen.

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What Makes Brufen Different?

One reason Brufen remains a commonly prescribed NSAID is its ability to provide pain relief, anti-inflammatory action and fever reduction in a single medicine. This combination makes it suitable for many conditions where inflammation is an important cause of pain.

However, it is not suitable for everyone. Brufen should not be combined with other NSAIDs such as naproxen or diclofenac unless specifically advised by a doctor, as this increases the risk of serious side effects.

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Key Takeaway

Brufen 400 mg Tablet is an effective anti-inflammatory medicine that helps relieve pain, swelling and fever caused by a wide variety of conditions. When taken responsibly at the recommended dose and for the shortest possible duration, it offers reliable symptom relief while maintaining a well-established safety profile. If symptoms persist, worsen or require long-term treatment, medical assessment is recommended to identify and manage the underlying cause.

Brufen 400 mg is primarily prescribed to relieve pain, reduce inflammation and lower fever in a wide range of conditions.

Common primary uses include:

• Osteoarthritis.
• Rheumatoid arthritis.
• Ankylosing spondylitis.
• Muscle pain.
• Joint pain.
• Back pain.
• Neck pain.
• Sports injuries.
• Sprains and strains.
• Dental pain and toothache.
• Headaches.
• Migraine attacks.
• Painful menstrual periods (dysmenorrhoea).
• Fever is associated with infections.

Brufen 400 mg should be taken exactly as prescribed by your doctor or according to the instructions on the product label. It is intended for short-term pain relief unless your healthcare professional recommends longer treatment for chronic inflammatory conditions.

Swallow the tablet whole with a full glass of water. Do not crush, chew or break the tablet unless advised by your healthcare provider.

To help reduce the risk of stomach irritation, Brufen should preferably be taken with food, immediately after a meal or with milk.

Tips for Safe Use

• Take Brufen only when needed or as prescribed.
• Use the lowest effective dose for the shortest possible duration.
• Leave the recommended interval between doses.
• Drink plenty of fluids during treatment, particularly if you have a fever or diarrhoea.
• Avoid taking Brufen with other NSAIDs unless advised by your doctor.
• If your symptoms do not improve or become worse, seek medical advice.

Before You Take Brufen 400 mg

Brufen 400 mg is an effective medicine for relieving pain and inflammation, but it is not suitable for everyone. Certain medical conditions, medicines and lifestyle factors can increase the risk of serious side effects. Before starting treatment, make sure your doctor or pharmacist knows about your medical history.

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Allergy

Do not take Brufen if you are allergic to ibuprofen, aspirin or any other non-steroidal anti-inflammatory drugs (NSAIDs).

Stop taking the medicine immediately and seek emergency medical help if you develop:

• Swelling of the face, lips, tongue or throat.
• Difficulty breathing or wheezing.
• Severe skin rash or hives.
• Sudden dizziness or fainting.

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Pregnancy

Brufen is not recommended during pregnancy, particularly after 20 weeks, unless your doctor considers it essential.

• During the first and second trimesters, it should only be used if the expected benefit outweighs the potential risks.
• During the third trimester, Brufen is contraindicated because it may harm the unborn baby, reduce amniotic fluid, delay labour and increase the risk of bleeding during delivery.

Pregnant women should consult their healthcare professional before taking any ibuprofen-containing medicine.

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Breastfeeding

Small amounts of ibuprofen pass into breast milk, but it is generally considered compatible with breastfeeding when used at the recommended dose for a short period.

Use the lowest effective dose for the shortest possible duration, and consult your doctor if prolonged treatment is required.

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Kidney Disease

Brufen may reduce blood flow to the kidneys, particularly in people who are dehydrated or already have kidney problems.

Use with caution if you:

• Have chronic kidney disease.
• Are taking diuretics.
• Have heart failure.
• Are older than 65 years.
• Are dehydrated due to diarrhoea or vomiting.

People with severe kidney impairment should generally avoid Brufen unless advised by a specialist.

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Liver Disease

People with liver disease should use Brufen carefully, as reduced liver function may increase the risk of adverse effects.

Consult your doctor before taking Brufen if you have:

• Hepatitis.
• Cirrhosis.
• Fatty liver disease.
• Abnormal liver function tests.

Stop taking the medicine and seek medical attention if you develop jaundice, dark urine or persistent upper abdominal pain.

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Heart Disease

Long-term use or high doses of Brufen may slightly increase the risk of heart attack or stroke, particularly in people with existing cardiovascular disease.

Speak to your doctor before using Brufen if you have:

• Coronary artery disease.
• Previous heart attack.
• Stroke.
• Heart failure.
• Peripheral arterial disease.

Use the medicine at the lowest effective dose for the shortest possible time.

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High Blood Pressure

Brufen may cause fluid retention and can reduce the effectiveness of some blood pressure medicines.

If you have hypertension, monitor your blood pressure regularly and consult your doctor before prolonged use.

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Asthma

Some people with asthma are sensitive to NSAIDs.

Avoid Brufen if you have ever experienced:

• Asthma attacks after taking aspirin.
• Wheezing after ibuprofen.
• NSAID-induced allergic reactions.

Seek immediate medical attention if breathing difficulties occur after taking the tablet.

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Stomach Ulcers and Bleeding

Brufen may irritate the stomach lining and increase the risk of ulcers or gastrointestinal bleeding.

The risk is higher if you:

• Have had a stomach ulcer before.
• Are over 65 years of age.
• Take corticosteroids or blood thinners.
• Consume excessive alcohol.

Seek urgent medical care if you notice black stools, vomiting blood or severe stomach pain.

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Elderly

Older adults are more likely to experience side effects from NSAIDs, particularly stomach bleeding, kidney impairment and cardiovascular complications.

Lower doses and close medical supervision may be appropriate.

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Children

Brufen 400 mg Tablets are generally intended for adults and adolescents aged 12 years and older.

For younger children, doctors usually recommend ibuprofen oral suspension or another paediatric formulation based on body weight.

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Alcohol

Avoid or limit alcohol while taking Brufen.

Combining alcohol with NSAIDs increases the risk of:

• Stomach irritation.
• Stomach ulcers.
• Gastrointestinal bleeding.
• Dizziness.

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Existing Medical Conditions

Speak to your doctor before taking Brufen if you:

• Have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
• Have systemic lupus erythematosus (SLE).
• Have a bleeding disorder.
• Have diabetes with kidney complications.
• Are planning surgery.
• Are trying to conceive, as ibuprofen may temporarily affect female fertility.

Important Safety Advice

Brufen 400 mg is intended to relieve pain, inflammation and fever, but it should be used responsibly. Do not exceed the recommended dose or duration of treatment, and avoid taking it with other NSAIDs unless specifically advised by your healthcare professional. If symptoms persist, worsen or you experience signs of stomach bleeding, chest pain, difficulty breathing or a severe allergic reaction, seek immediate medical attention.

Brufen 400 mg contains ibuprofen, a non-steroidal anti-inflammatory drug (NSAID). Use the lowest effective dose for the shortest time needed to control symptoms. Taking Brufen for prolonged periods or at higher doses may increase the risk of stomach ulcers, gastrointestinal bleeding, kidney problems and cardiovascular complications. Do not take Brufen together with other NSAIDs, including ibuprofen-containing products, unless advised by your doctor. Seek immediate medical attention if you develop severe stomach pain, black stools, vomiting blood, chest pain, difficulty breathing or signs of a severe allergic reaction.

Like all medicines, Brufen 400 mg can cause side effects, although many people take it without experiencing any problems. Most side effects are mild and temporary, particularly when the medicine is used at the lowest effective dose for a short period.

The most common side effects affect the digestive system, as ibuprofen may irritate the stomach lining.

Common side effects include:

• Indigestion (dyspepsia)
• Heartburn
• Stomach pain or discomfort
• Nausea
• Vomiting
• Diarrhoea
• Constipation
• Bloating or wind
• Headache
• Dizziness
• Mild drowsiness
• Skin rash
• Itching
• Mild swelling of the hands or feet due to fluid retention

These side effects are usually mild and often improve after stopping the medicine or taking it with food. If they become persistent or troublesome, speak with your doctor or pharmacist.

Proper storage helps maintain the quality, safety and effectiveness of Brufen 400 mg Tablets. Always store the medicine according to the instructions on the packaging and keep it out of the reach of children.

Storage Conditions

• Store at room temperature, preferably below 25°C.
• Keep the tablets in their original blister pack or carton until needed.
• Protect the medicine from moisture, excessive heat and direct sunlight.
• Store in a cool, dry place away from bathrooms, kitchen sinks and other damp areas.
• Keep out of the sight and reach of children and pets.
• Do not use Brufen after the expiry date printed on the packaging.

Disposal

If your treatment has finished or the tablets have expired:

• Do not throw them into household waste or flush them down the toilet.
• Return unused or expired tablets to a pharmacy for safe disposal whenever possible.
• Follow your local medicine disposal guidelines to help protect the environment.

Important: Do not use tablets that appear damaged, discoloured or have been stored improperly.

10 tablets